Material Safety Data Sheet for Vanadium Nicotinate

Identification

Product Name: Vanadium Nicotinate
Chemical Synonyms: Vanadyl Nicotinate, Vanadium Pyridine-3-Carboxylate Complex
Recommended Use: Laboratory research, trace mineral supplement in livestock nutrition, manufacturing intermediate
Manufacturer Information: Listed on packaging, customer service provided by licensed suppliers
Contact Numbers: Emergency and information lines available via supplier label
CAS Number: 13446-09-6 for Vanadium compounds; specific for Vanadium Nicotinate may vary by registry and supplier
UN Number: Non-regulated unless concentrated or mixed with hazardous solvents
Formula: C6H4NO2·VO, complex salt
Emergency Overview: Slightly bluish powder with faint odor; dust may irritate eyes and respiratory tract

Hazard Identification

GHS Classification: Acute Toxicity (Oral Category 4), Skin Irritant (Category 2), Eye Irritant (Category 2A), Specific Target Organ Toxicity – Repeated Exposure (STOT-RE Category 2) for vanadium effects
Signal Word: Warning
Hazard Statements: Harmful if swallowed; may cause irritation to eyes, respiratory system, and skin; prolonged exposure at high levels may affect kidneys, liver, or blood system; may cause allergic reactions in sensitive individuals
Pictograms: Exclamation mark
Precautionary Statements: Avoid contact with eyes and skin; wash hands thoroughly after handling; do not eat, drink, or smoke during use
Routes of Exposure: Inhalation, ingestion, skin and eye contact
Health Effects: Mild inhalation of dust may cause coughing or throat irritation; accidental ingestion can upset stomach, cause nausea and headaches; people with respiratory conditions can be more sensitive

Composition / Information on Ingredients

Chemical Name: Vanadium Nicotinate
Concentration: Typically > 95% by weight
Components: Vanadium (oxidation state +4, as vanadyl ion), Nicotinic acid ligand
Impurities: Trace amounts of pyridine, vanadium oxides, nonhazardous binders possible
Ingredient List: No hazardous stabilizers or solvents used in preparation
Molecular Weight: ~205–250 g/mol (complex dependent on hydration)
Other Identification: EINECS/ELINCS: Refer to supplier registration

First Aid Measures

Inhalation: Move to fresh air immediately; seek medical attention if coughing, shortness of breath, or dizziness persists
Skin Contact: Wash thoroughly with soap and water; remove contaminated clothing; consult a healthcare provider for persistent irritation
Eye Contact: Rinse cautiously with water for at least 15 minutes, holding eyelids open; seek medical evaluation if pain or redness remains
Ingestion: Rinse mouth; do not induce vomiting; seek medical help if symptoms develop such as stomach pain, nausea, or dizziness
Medical Attention: Provide chemical name and SDS to emergency responders; treat symptoms supportively; monitor breathing and vital signs
Special Advice for Doctors: Biomonitor vanadium and monitor renal and hepatic function if high-level exposure suspected

Fire-Fighting Measures

Flammability: Nonflammable under normal conditions
Suitable Extinguishing Media: Use water spray, CO2, dry chemical, or foam for surrounding fire; Vanadium Nicotinate itself will not fuel flames
Unsuitable Media: Avoid strong water jets, which can spread dust
Specific Hazards: May release toxic fumes of vanadium oxides and nitrogen oxides at high temperatures
Advice for Firefighters: Wear self-contained breathing apparatus and full protective gear; avoid inhaling fumes
Special Procedures: Keep containers cool with water if exposed to fire; isolate area due to possible toxic dust or decomposition products
Explosion Data: No explosion hazard reported

Accidental Release Measures

Personal Precautions: Wear safety goggles, gloves, and dust mask or respirator; ventilate area to disperse airborne dust
Methods for Cleanup: Clean up carefully to avoid creating dust; sweep up and dispose of in closed containers; use damp cloth for residual particles
Environmental Precautions: Prevent spillage from reaching drains, soil, or water systems
Decontamination: Wash affected surfaces with mild detergent; avoid high-pressure water streams
Notification: Report large spills to local environmental or health authorities if required
Disposal: Place waste in labeled chemical disposal containers, awaiting proper waste processing

Handling and Storage

Handling: Minimize dust generation and accumulation; avoid direct contact with skin, eyes, and clothing; use fume hood or local exhaust where practical
Storage Conditions: Store in tightly closed containers in a cool, dry, well-ventilated area; keep away from oxidizers and acids
Storage Temperature: Room temperature recommended; avoid temperature extremes
Incompatibilities: Strong acids, oxidizers, reducing agents
Hygiene: Wash hands thoroughly after handling; do not eat, drink, or smoke in work areas
Other Precautions: Store only in labeled containers; prevent contact with food, feed, and drinking water supplies

Exposure Controls and Personal Protection

Occupational Exposure Limits: OSHA/NIOSH limit for vanadium (as V): 0.05 mg/m³ (respirable dust, TWA)
Engineering Controls: Local exhaust ventilation; safety showers and eyewash stations required
Personal Protection:
Eye/Face: Safety goggles with side shields
Skin: Chemically resistant gloves (e.g., nitrile, neoprene)
Body: Lab coats, aprons where splash risk exists
Respiratory: Use NIOSH-approved particulate respirator in dust-generating work
Environmental Controls: Avoid discharge into sewers; use spill control and proper disposal
Workplace Practices: Change contaminated clothing; maintain regular housekeeping

Physical and Chemical Properties

Appearance: Light blue to green crystalline powder
Odor: Faint, slightly musty
Odor Threshold: Not established
pH: 4–6 in aqueous suspension
Melting Point/Range: Decomposes before melting, above 200°C
Boiling Point: Not applicable (decomposes)
Flash Point: Not applicable
Evaporation Rate: Not available
Flammability: Not flammable
Solubility: Slightly soluble in water; soluble in dilute mineral acids
Vapor Pressure: Negligible at room temperature
Density: 1.5–1.8 g/cm³
Partition coefficient (n-octanol/water): Not established
Decomposition Temperature: Above 200°C with formation of toxic oxides
Other Data: Stable in closed containers under recommended conditions

Stability and Reactivity

Chemical Stability: Stable under normal storage and handling conditions
Reactivity: May hydrolyze in strong acidic or basic solutions
Incompatible Materials: Strong oxidizing agents (e.g., peroxides), strong acids (release toxic fumes), strong bases
Hazardous Polymerization: Will not occur
Decomposition Products: Vanadium oxides (VOx), nitrogen oxides (NOx), carbon oxides
Conditions to Avoid: Excess heat, moisture, dust formation

Toxicological Information

Acute Toxicity: Oral LD50 (rat): approximately 500–1,000 mg/kg for vanadium compounds
Skin Corrosion/Irritation: Mild irritant in sensitive individuals
Serious Eye Damage/Irritation: May cause redness and pain
Respiratory Sensitization: High dust concentrations can trigger upper respiratory symptoms
Chronic Effects: Prolonged exposure to vanadium dusts linked to kidney, liver, and blood effects in industrial workers
Carcinogenicity: Not listed by NTP, OSHA, or IARC as carcinogenic
Mutagenicity/Teratogenicity: No conclusive studies for Vanadium Nicotinate
Other Health Effects: Chronic ingestion associated in some studies with minor anemia, gastrointestinal irritation; further research continues in occupational and environmental health fields

Ecological Information

Ecotoxicity: Vanadium compounds show moderate toxicity toward aquatic organisms; data for Vanadium Nicotinate itself limited
Persistence and Degradability: Degrades slowly in soil and water; disperses as ions/complexes
Bioaccumulation: Potential for bioaccumulation in aquatic species at sustained exposure; routine monitoring recommended in disposal
Mobility in Soil: Mobile under certain pH conditions; more persistent in alkaline or neutral soils
Other Adverse Effects: Avoid uncontrolled discharges; sustained releases could disrupt aquatic and terrestrial ecosystems

Disposal Considerations

Waste Treatment Methods: Handle as hazardous chemical waste; prevent entering sewage or natural waterways
Disposal Containers: Use leakproof, clearly labeled chemical waste drums
Recommended Disposal: Dispose through licensed chemical waste contractors; landfilling or incineration in permitted facilities whenever required by local regulation
Recycling/Reuse: Not suitable for recycling; do not reintroduce into general waste streams
Regulatory Considerations: EPA, local and national environmental guidelines apply
Special Precautions: Wear gloves, mask, and other recommended PPE during handling of waste

Transport Information

UN Number: Not classified as dangerous for ground transport in small quantities
Proper Shipping Name: Vanadium Compound, n.o.s.
Transport Hazard Class: Not applicable, unless mixed or formulated with hazardous solvents
Packing Group: None required for dry powder
Labeling: Chemical name, hazard pictograms, supplier identification, and batch/lot number
Environmental Hazards: Not a marine pollutant in small packaged quantities
Special Transportation Precautions: Secure containers to prevent release; avoid exposure to moisture

Regulatory Information

Inventory Status: Listed in TSCA (US), EINECS (EU), DSL (Canada)
OSHA/SARA: OSHA hazardous chemical, vanadium subject to SARA Section 313 reporting for certain uses
EPA: Regulated under RCRA for certain concentrations; observe regulatory disposal requirements
WHMIS (Canada): D2B—Toxic Material Causing Other Toxic Effects
State Regulations: Check California Proposition 65, Massachusetts/Right-to-Know, and other state listings for vanadium compounds
Label Requirements: Comply with GHS and local regulations—hazard pictograms and risk phrases as specified
Other Regulations: Transport, use, and disposal restrictions apply in occupational settings; consult local, state, and national regulatory guidelines for details