MSDS: Hydroxy Selenomethionine

1. Identification

Product Name: Hydroxy Selenomethionine
Chemical Formula: C5H11NO2Se
CAS Number: 34449-06-6
Synonyms: 2-Amino-4-(hydroxyseleno)butyric acid, Selenomethionine hydroxide
Recommended Use: Animal feed additive, nutritional supplement
Manufacturer's Contact: Contact details from supplier or manufacturer; emergency phone numbers provided with shipping documents and safety information
Address: Listed on container and invoice
Relevant Identified Uses: Industrial, research, feed industry applications

2. Hazard Identification

Classification: Acute toxicity (oral, dermal, inhalation) Category 3; Hazardous to aquatic environment, acute Category 2
Signal Word: Danger
Hazard Statements: Toxic if swallowed; Toxic by skin contact; Harmful if inhaled; May cause organ damage through prolonged or repeated exposure; Harmful to aquatic life
Pictograms: Skull and crossbones, exclamation mark, environment
Precautionary Statements: Avoid breathing dust or vapors; Wash hands thoroughly after handling; Do not eat, drink, or smoke during use; Avoid release to environment; Wear protective gloves, clothing, and eye protection

3. Composition / Information on Ingredients

Chemical Name: Hydroxy Selenomethionine
Percent Purity: ≥98%
Molecular Weight: 196.10 g/mol
Component: Single ingredient product, not present with diluents or carrier materials unless specified

4. First Aid Measures

General Advice: Move affected person to fresh air and keep at rest; perform immediate decontamination
If Inhaled: Remove person to fresh air, seek medical attention for respiratory distress, administer oxygen if breathing is difficult
Skin Contact: Rinse with soap and water for several minutes, remove contaminated clothing and shoes
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses if present and easy to do
If Swallowed: Rinse mouth, do not induce vomiting, seek immediate medical attention
Immediate Medical Attention Required: Ingestion or symptomatic exposure may require observation and treatment in a hospital environment
Most Important Symptoms/Effects: Shortness of breath, abdominal pain, headache, signs of selenium toxicity such as garlic breath, gastrointestinal upset, loss of hair, neurological symptoms at higher exposures

5. Fire-Fighting Measures

Suitable Extinguishing Media: Water spray, carbon dioxide, dry chemical powder, foam
Specific Hazards During Fire: Emits toxic fumes of selenium oxides, nitrogen oxides, carbon monoxide, and carbon dioxide
Special Protective Equipment: Firefighters should wear full protective clothing and self-contained breathing apparatus
Firefighting Procedures: Remain upwind, keep out of smoke, use water spray to cool unaffected containers, prevent runoff to waterways
Explosion Data: Product not known to be explosive, fine powder may present dust explosion hazard in unventilated areas

6. Accidental Release Measures

Personal Precautions: Wear protective clothing, respiratory protection, gloves, safety goggles
Environmental Precautions: Prevent product from entering storm drains, sewers, and waterways; notify appropriate authorities of significant contamination
Clean-Up Methods: Vacuum or sweep up material gently without raising dust, place in appropriate waste container
Decontamination: Clean area thoroughly with water, ventilate the site
Disposal: Observe all federal, state, and local regulations on disposal; consult waste contractor if necessary

7. Handling and Storage

Handling: Wear protective gear, avoid breathing dust or contact with skin and eyes
Hygiene Practices: Wash hands before breaks and after use; keep work area clean; avoid eating, drinking, or smoking in the work area
Storage Conditions: Store in tightly closed container in cool, dry, well-ventilated place; protect from heat, moisture, and incompatible materials; ensure proper labeling and secure location; prevent unauthorized access

8. Exposure Controls and Personal Protection

Exposure Limits: OSHA PEL (Selenium compounds, as Se): 0.2 mg/m³ TWA; ACGIH TLV: 0.2 mg/m³ TWA
Engineering Controls: Use local exhaust ventilation, closed systems or work under fume hood to minimize exposure
Personal Protective Equipment: Dust mask or respirator (NIOSH-approved if necessary); chemical safety goggles; impermeable gloves (nitrile, neoprene); lab coat or disposable coveralls
Environmental Controls: Avoid release to the environment; use spill containment and proper waste disposal procedures
Monitoring Requirements: Periodic workplace air monitoring, medical surveillance for those with sustained exposure

9. Physical and Chemical Properties

Form: Crystalline powder
Color: White to off-white
Odor: Slight characteristic or garlic-like odor due to selenium content
Melting Point: 266-270°C (dec.)
Boiling Point: Not applicable, decomposes
Solubility: Slightly soluble in water
pH: Not determined in aqueous solution
Vapor Pressure: Not applicable
Specific Gravity: Approximately 1.5
Partition Coefficient (n-octanol/water): Not available
Autoignition Temperature: Not determined

10. Stability and Reactivity

Chemical Stability: Stable under recommended storage conditions
Hazardous Reactions: No dangerous reactions known under normal use
Conditions to Avoid: Heat, exposure to light and air, proximity to strong oxidizing reagents
Incompatible Materials: Strong acids, strong oxidizing agents, halogenated compounds
Hazardous Decomposition Products: Selenium oxide, nitrogen oxides, carbon monoxide, carbon dioxide
Polymerization: Not expected to occur

11. Toxicological Information

Routes of Exposure: Inhalation, ingestion, dermal contact
Acute Toxicity: Oral LD50 (rat) estimated 10-55 mg/kg; may cause gastric upset, nausea, vomiting
Chronic Toxicity: Prolonged exposure can cause symptoms of selenium toxicity (selenosis): gastrointestinal disturbance, loss of hair, weakened nails, metallic taste
Skin Irritation: Possible mild to moderate irritation
Eye Irritation: May cause irritation and redness
Sensitization: Data not conclusive
Carcinogenicity: Not classified as carcinogenic by IARC, NTP, or OSHA; selenium is an essential element but toxic in excess
Reproductive Effects: Developmental effects not established at low levels; high doses are toxic

12. Ecological Information

Ecotoxicity: Highly toxic to aquatic life; may cause bioaccumulation in aquatic organisms; chronic selenium exposure in wildlife is associated with reproductive effects and teratogenicity
Persistence and Degradability: Selenium persists in the environment, may not degrade biologically
Bioaccumulation Potential: Likely to bioaccumulate, especially in aquatic food webs
Mobility in Soil: Moderate; ionic forms migrate with water, organic forms may be less mobile
Other Adverse Effects: Entry into the environment should be strictly controlled

13. Disposal Considerations

Disposal Methods: Collect and dispose of in accordance with local, regional, and national regulations; incineration in chemical waste facility preferred
Container Disposal: Empty containers should be triple-rinsed or decontaminated before disposal or recycling; avoid uncontrolled dumping
Special Precautions: Manage selenium-containing waste as hazardous waste, prevent release to soil, drains, or surface waters

14. Transport Information

UN Number: UN 3283
Proper Shipping Name: Toxic solid, inorganic, n.o.s. (Hydroxy Selenomethionine)
Transport Hazard Class: 6.1 (Toxic Substances)
Packing Group: II
Marine Pollutant: Applicable; avoid shipment in bulk by sea
DOT, IMDG, IATA Regulations: All require appropriate labeling, packaging, and documentation
Special Precautions for User: Follow all transport regulations; keep away from food and animal feeds in transit

15. Regulatory Information

OSHA Hazard Communication: Regulated as a hazardous chemical
TSCA Inventory: Listed
SARA Title III: Subject to reporting under Sections 302, 311, 312, and 313 for selenium compounds
RCRA: Selenium waste streams may qualify as hazardous waste (D010)
Other State/Federal Regulations: Relevant reporting and handling requirements apply, including those for hazardous substances under CERCLA
EU Classification: T+ (very toxic), N (dangerous for the environment); risk phrases R23/25, R33, R50/53
Workplace Labeling: Clear hazard statements, emergency contacts, and protective measures should appear on all workplace labels and shipping containers